Effect of Zn addition on sol-gel derived apatite/wollastonite glass-ceramics scaffolds

Authors

  • S. Tubsungneon Rattanachan
  • N. Srakaew
  • R. Pethnin
  • N. Suppakarn

Abstract

Bioactive glasses and glass-ceramics consisting of CaO-MgO-P2O5-SiO2 system have been shown tobe bioactive, resorbable and to exhibit appropriate mechanical properties for bone tissue engineeringapplications. Bioactive glass-ceramics scaffolds consisting of zinc doped-apatite/wollastonite (AW) glassceramicswere prepared by coating polyurethane foams with sol-gel derived glass gels. Density andcompressive strength of the scaffolds decreased with increased in zinc contents. In vitro bioactivity of ZndopedAW glass-ceramics in a simulated body fluid (SBF) showed the formation of apatite layer on thesurface within 7 days of soaking. However, increasing Zn addition increased the chemical durability of theAW glass-ceramics, resulting in a decrease in the rate of apatite formation in a simulated body fluid. Withobservation by SEM technique microstructure of pores showed interconnected macropores in the range of 300-500 ?m as depended on the type of sponge. Average pore size increased with increasing the zincadditions. Macropores and interconnect size can be tailored by controlling the zinc concentrations.

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Published

2012-12-23

How to Cite

[1]
S. Tubsungneon Rattanachan, N. Srakaew, R. Pethnin, and N. Suppakarn, “Effect of Zn addition on sol-gel derived apatite/wollastonite glass-ceramics scaffolds”, J. Met. Mater. Miner., vol. 22, no. 2, Dec. 2012.

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Original Research Articles