Methyl methacrylate magnetic molecularly imprinted polymer for gluten determination

ผู้แต่ง

  • Dalawan Limthin College of Nanotechnology, King Mongkut’s Institute of Technology Ladkrabang
  • Kunanon Chattrairat College of Nanotechnology, King Mongkut’s Institute of Technology Ladkrabang
  • Pitawan Leepheng king mongkut's institute of technology ladkrabangCollege of Nanotechnology, King Mongkut’s Institute of Technology Ladkrabang
  • Sawita Wisutthipat king mongkut's institute of technology ladkrabangCollege of Nanotechnology, King Mongkut’s Institute of Technology Ladkrabang
  • Poompun Gansa College of Nanotechnology, King Mongkut’s Institute of Technology Ladkrabang
  • Annop Klamchuen National Nanotechnology Center, National Science and Technology Development Agency
  • Darinee Phromyothin College of Nanotechnology, King Mongkut’s Institute of Technology Ladkrabang

คำสำคัญ:

Gluten, Magnetic molecularly imprinted polymers, Electrochemical analysis

บทคัดย่อ

The gluten protein is found in some rice and flour. The allergy of gluten, a little bit of gluten in diet cause long-term damage and dangerous to the body. Even tiny amounts of gluten in diet may bring enormous symptoms. The rapid and simple method for gluten detection is molecularly imprinted polymers (MIP) combined with electrochemical analysis. In addition, magnetic molecularly imprinted polymers (MMIP) as known as Fe3O4 magnetic nanoparticles have used in combination with electrochemical measurement as well to improve the sensitivity of detection. In this work, the MMIP was combined with electrochemical technique. The Fe3O4 magnetic nanoparticles were synthesized by chemical reaction and then encapsulated with methyl methacrylate (MMA) as a functional group for gluten detection. Dynamic light scattering measurement clearly illustrates the average size of as-synthesized Fe3O4 nanoparticles as low as 150 nm. Chemical bonding, morphology, crystal structure and magnetic properties were characterized by fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM), X-ray diffractometer (XRD), and vibrating sample magnetometer (VSM), respectively.

Downloads

Download data is not yet available.

เอกสารอ้างอิง

Z. Weibiao, Y. H. Hui, I. De Leyn, M. A. Pagani, C. M. Rosell, J. D. Selman, and N. Therdthai, Bakery Products Science and Technology. Wiley-Blackwell, John Wiley & Sons, Ltd., 2014.

J. B. Roses, “Food allergen law and the food allergen labeling and consumer protection act of 2004: Falling short of true protection for food allergy sufferers,” Food and drug law journal, vol. 66, pp. 225-242, 2011.

H. Deutsch, R. Poms, H. Heeres, J.-W. van der Kamp, 2 - Labeling and regulatory issues, in: E.K. Arendt, F. Dal Bello (Eds.), “GlutenFree Cereal Products and Beverages,” Academic Press, San Diego, pp.29-46, 2008.

P. Mansueto, A. Seidita, A. D'Alcamo, and A. Carroccio, “Non-celiac gluten sensitivity: literature review,” Journal of the American College of Nutrition, vol.33, pp. 39-54, 2014.

C. Don and P. Koehler, “Enzyme-Linked Immunosorbent Assays for the Detection and Quantitation of Gluten in Cereal-Based Foods,” Cereal Foods World, vol. 59, pp. 171-178, 2014.

L. Stephen, “Gluten detection and speciation by liquid chromatography mass spectrometry (LC-MS/MS),” Foods, vol. 3, pp. 13-29, 2014.

M. L. Colgrave, H. Goswami, M. Blundell, C. A. Howitt, and G. J. Tanner, “Using mass spectrometry to detect hydrolysed gluten in beer that is responsible for false negatives by ELISA,” Journal of Chromatography A, vol. 1370, pp. 105-114, 2014.

Y. Qian, K. Preston, O. Krokhin, J. Mellish, and W. Ens, “Characterization of wheat gluten proteins by HPLC and MALDI TOF mass spectrometry,” Journal of the American Society for Mass Spectrometry, vol. 19, pp. 1542-50, 2008.

K. A. Scherf, “Impact of the preparation procedure on gliadin, glutenin and gluten contents of wheat starches determined by RPHPLC and ELISA,” European Food Research and Technology, vol. 242, pp. 1837-1848, 2016.

V. V. Shumyantseva, E. V. Suprun, T. V. Bulko, and A. I. Archakov, “Electrochemical methods for detection of post-translational modifications of proteins,” Biosens Bioelectron, vol. 61, pp. 131-139, 2014.

M. Labib, E. H. Sargent, and S. O. Kelley, “Electrochemical Methods for the Analysis of Clinically Relevant Biomolecules,” Chemical Review, vol. 116, pp. 9001-9090, 2016.

S. A. González, N. de-los-S.-Álvarez, A. J. Miranda-Ordieres, and M. J. Lobo-Castañón, “Sensitive gluten determination in glutenfree foods by an electrochemical aptamerbased assay,” Analytical and Bioanalytical Chemistry, vol. 407, pp. 6021-6029, 2015.

E. Eksin, G. Congur, and A. Erdem, “Electrochemical assay for determination of gluten in flour samples,” Food Chemistry, vol. 184, pp. 183-187, 2015.

R. Gui, H. Jin, H. Guo, and Z. Wang. “Recent advances and future prospects in molecularly imprinted polymers-based electrochemical biosensors,” Biosensors and Bioelectronics, vol. 100, pp. 56-70, 2018.

M. Dabrowski, P. Lach, M. Cieplak, and W. Kutner, “Nanostructured molecularly imprinted polymers for protein chemosensing,” Biosensors and Bioelectronics, vol. 102, pp. 17-26, 2018.

P. Yáñez-Sedeño, S. Campuzano, and J. M. Pingarrón, “Electrochemical sensors based on magnetic molecularly imprinted polymers: A review,” Analytica Chimica Acta, vol. 960, pp. 1-17, 2017.

S. Ansari “Application of magnetic molecularly imprinted polymer as a versatile and highly selective tool in food and environmental TrAC Trends in Analytical Chemistry, vol. 90, pp. 89-106 2017.

Z. Zhang, L. Luo, R. Cai, H. Chen, “A sensitive and selective molecularly imprinted sensor combined with magnetic molecularly imprinted solid phase extraction for determination of dibutyl phthalate,” Biosensors and Bioelectronics, vol. 49, pp. 367-373, 2013.

S. Kumar, P. Karfa, S. Patra, R. Madhuri, and P. K. Sharma, “Molecularly imprinted star polymer-modified superparamagnetic iron oxide nanoparticle for trace level sensing and separation of mancozeb,” Royal Society of Chemistry Advances, vol. 6, pp. 36751- 36760, 2016.

M. Tajabadi, M. E. Khosroshahi, and S. Bonakdar, “Anefficient method of SPION synthesis coated with third generation PAMAM dendrimer,” Colloids and Surfaces A: Physicochemical and Engineering Aspects, vol. 431, pp. 18-26, 2013.

S. Yoffe, T. Leshuk, P. Everett, and F. Gu, “Superparamagnetic iron oxide nanoparticles (SPIONs): synthesis and surface modification techniques for use with MRI and other biomedical applications,” Current Pharmaceutical Design, vol. 19, pp. 493-509, 2013.

Y. Wei, B. Han, X. Hu, L. Yuanhua, X. Wang, and X. Deng, “Synthesis of Fe3O4 nanoparticles and their magnetic properties,” Procedia Engineering, vol. 27, pp. 632-637, 2012.

F. Ortolan and C. J. Steel, “Protein characteristics that affect the quality of vital wheat gluten to be used in baking: A review,” Comprehensive Reviews in Food Science and Food Safety, vol. 16, pp. 369-381, 2017.

A. Shrivastava and V. B. Gupta, “Methods for the determination of limit of detection and limit of quantitation of the analytical methods” Chronicles of Young Scientists, vol. 2, pp. 21-25, 2011.

ดาวน์โหลด

เผยแพร่แล้ว

2019-03-29

วิธีการอ้างอิง

[1]
D. Limthin, “Methyl methacrylate magnetic molecularly imprinted polymer for gluten determination”, J Met Mater Miner, ปี 29, ฉบับที่ 1, มี.ค. 2019.

ฉบับ

บท

Original Research Articles