Natural wound dressing films prepared from acetylated starch/κ-carrageenan blend incorporated with mandelic acid

Authors

  • Wimolsiri SRIPHOCHAI Department of Chemistry, School of Science, King Mongkut’s Institute of Technology Ladkrabang (KMITL), Bangkok 10520, Thailand
  • Jutarat PRACHAYAWARAKORN Department of Chemistry, School of Science, King Mongkut’s Institute of Technology Ladkrabang (KMITL), Bangkok 10520, Thailand; Advanced Materials Research Unit, School of Science, King Mongkut’s Institute of Technology Ladkrabang (KMITL), Bangkok 10520, Thailand https://orcid.org/0000-0001-7875-6981

DOI:

https://doi.org/10.55713/jmmm.v34i2.1984

Keywords:

Acetylated starch, κ-Carrageenan, Mandelic acid, Modification, Wound dressing

Abstract

Due to several limitations of acetylated starch film for wound dressing applications such as low mechanical properties and no antibacterial activity, acetylated starch film was, therefore, modified by different contents of κ-carrageenan and mandelic acid. Infrared spectra confirmed the presence of κ-carrageenan and mandelic acid in the modified acetylated starch films. In addition, the decreased crystallinity of the carrageenan modified acetylated starch films led to more smooth film, as observed by scanning electron images. Besides, the addition of various amounts of κ-carrageenan in the modified acetylated starch films caused the improvement of mechanical properties, moisture uptake, water vapor transmission rate (WVTR), and degree of swelling. Moreover, κ-carrageenan modified acetylated starch film loaded with 20 wt% of mandelic acid exhibited antibacterial property against both S.aureus and E.coli bacteria. Additionally, degree of crystallinity, mechanical properties, moisture uptake, WVTR, degree of swelling, antibacterial activity, and cytotoxicity of κ-carrageenan modified acetylated starch films added by different amounts of mandelic acid were also studied.

Downloads

Download data is not yet available.

References

H. R. Rashdan and M. E. El-Naggar, "Traditional and modern wound dressings—characteristics of ideal wound dressings," in Antimicrobial Dressings, K. Raju and G. Sorna, Eds. Massachusetts: Academic Press, 2023, pp. 21-41.

I. Savencu, S. Iurian, A. Porfire, C. Bogdan, and I. Tomuță, "Review of advances in polymeric wound dressing films," Reactive and Functional Polymers, vol. 168, p. 105059, 2021.

C. Wang, Y. Lu, Z. Li, X. An, Z. Gao, and S. Tian, "Preparation and performance characterization of a composite film based on corn starch, κ-carrageenan, and ethanol extract of onion skin," Polymers, vol. 14, no. 15, p. 2986, 2022.

S. Chuayjuljit, S. Hosililak, and A. Athisart, "Thermoplastic cassava starch/sorbitol-modified montmorillonite nanocomposites blended with low density polyethylene: properties and bio-degradability study," Journal of Metals, Materials and Minerals, vol. 19, 2009.

R. Colussi, S. L. M. El Halal, V. Z. Pinto, J. Bartz, L. C. Gutkoski, E. da Rosa Zavareze and A. R. G. Dias, "Acetylation of rice starch in an aqueous medium for use in food," LWT - Food Science and Technology, vol. 62, no. 2, pp. 1076-1082, 2015.

F. Han, M. Liu, H. Gong, S. Lü, B. Ni, and B. Zhang, "Synthesis, characterization and functional properties of low substituted acetylated corn starch," International Journal of Biological Macromolecules, vol. 50, no. 4, pp. 1026-1034, 2012.

A. Ayucitra, "Preparation and characterisation of acetylated corn starches," International Journal of Chemical Engineering and Applications, vol. 3, no. 3, p. 156, 2012.

I. A. Wani, D. S. Sogi, and B. S. Gill, "Physico-chemical properties of acetylated starches from Indian black gram (Phaseolus mungo L.) cultivars," Journal of food science and technology, vol. 52, pp. 4078-4089, 2015.

S. Mehboob, T. M. Ali, M. Sheikh, and A. Hasnain, "Effects of cross linking and/or acetylation on sorghum starch and film characteristics," International journal of biological macromolecules, vol. 155, pp. 786-794, 2020.

N. E. Kochkina, O. A. Butikova, and N. D. Lukin, "Ecofriendly films based on low-substituted starch acetate enhanced by polyvinyl alcohol additions," Iranian Polymer Journal, vol. 31, no. 11, pp. 1361-1371, 2022.

E. J. Jiménez-Regalado, C. Caicedo, A. Fonseca-García, C. C. Rivera-Vallejo, and R. Y. Aguirre-Loredo, "Preparation and physicochemical properties of modified corn starch–chitosan biodegradable films," Polymers, vol. 13, no. 24, p. 4431, 2021.

R. O. Sonawane, and S. D. Patil, "Gelatin–κ-carrageenan polyelectrolyte complex hydrogel compositions for the design and development of extended-release pellets," International Journal of Polymeric Materials and Polymeric Biomaterials, vol. 66, no. 16, pp. 812-823, 2017.

E. Abdou, and M. Sorour, "Preparation and characterization of starch/carrageenan edible films," International food research journal, vol. 21, no. 1, pp. 189-193, 2014.

Y. Zhou, F.-Q. Chen, S. Chen, Q. Xiao, H.-F. Weng, Q.-M. Yang, and A.-F. Xiao, "Preparation and characterization of κ-carrageenan modified with maleic anhydride and its application in films," Marine Drugs, vol. 19, no. 9, p. 486, 2021.

S. Mohandoss, S. Ganesan, K. Velsankar, S. Sudhahar, F. H. Alkallas, A. B. G. Trabelsi, F. V. Kusmartsev, H. M. Lo and Y. R. Lee, "Fabrication and characterization of Ag nanoparticle-embedded kappa-Carrageenan-Sodium alginate nanocomposite hydrogels with potential antibacterial and cytotoxic activities," Journal of Biomaterials Science, Polymer Edition, vol. 34, no. 6, pp. 715-733, 2023.

A. C. Flores, E. R. Punzalan, and N. G. Ambangan, "Effects of kappa-carrageenan on the physico-chemical properties of thermoplastic starch," Kimika, vol. 26, no. 1, pp. 10-16, 2015.

J. W. Rhim, "Physical‐mechanical properties of agar/κ‐carrageenan blend film and derived clay nanocomposite film," Journal of Food Science, vol. 77, no. 12, pp. 66-73, 2012.

C. de Lima Barizão, M. I. Crepaldi, S. Oscar de Oliveira, A. C. de Oliveira, A. F. Martins, P. S. Garcia and E. G. Bonafé, "Biodegradable films based on commercial κ-carrageenan and cassava starch to achieve low production costs," International Journal of Biological Macromolecules, vol. 165, pp. 582-590, 2020.

D. Tungmunnithum, A. Thongboonyou, A. Pholboon, and A. Yangsabai, "Flavonoids and other phenolic compounds from medicinal plants for pharmaceutical and medical aspects: An overview," Medicines, vol. 5, no. 3, p. 93, 2018.

O. Zavyalova, S. Gajewska, D. Dąbrowska-Wisłocka, and A. Sionkowska, "Characteristics of physicochemical and rheological properties of chitosan hydrogels based on selected hydroxy acids," Engineering of Biomaterials, vol. 24, no. 161, 2021.

R. Kumar and P. Rani, "Mandelic acid incorporated antimicrobial soy protein film fabricated by solution casting," in Advances in Polymer Sciences and Technology, Materials Horizons: From Nature to Nanomaterials, B. Gupta, A. Ghosh, A. Suzuki, S. Rattan, Eds. Singapore: Springer, 2018, pp. 13-19.

R. Kumar, R. D. Anandjiwala, and A. Kumar, "Thermal and mechanical properties of mandelic acid-incorporated soy protein films," Journal of Thermal Analysis and Calorimetry, vol. 123, no. 2, pp. 1273-1279, 2015.

M. Motamedifar, A. Bazargani, M. R. Namazi, E. Sarai, and H. Sedigh, "Antimicrobial activity of mandelic acid against methicillin-resistant Staphylococcus aureus: a novel finding with important practical implications," World Applied Sciences Journal, vol. 31, no. 5, pp. 925-929, 2014.

C. S. Raina, S. Singh, A. S. Bawa, and D. C. Saxena, "Some characteristics of acetylated, cross-linked and dual modified Indian rice starches," European Food Research and Technology, vol. 223, no. 4, pp. 561-570, 2006.

D. Kalita, N. Kaushik, and C. L. Mahanta, "Physicochemical, morphological, thermal and IR spectral changes in the properties of waxy rice starch modified with vinyl acetate," Journal of Food Science and Technology, vol. 51, pp. 2790-2796, 2014.

A. H. D. Abdullah, S. Chalimah, I. Primadona, and M. H. G. Hanantyo, "Physical and chemical properties of corn, cassava, and potato starchs," IOP Conference Series: Earth and Environmental Science, vol. 160, p. 012003, 2018.

R. Wang, S. Zhang, S. Liu, Y. Sun, and H. Xu, "A contribution to improve barrier properties and reduce swelling ratio of κ-carrageenan film from the incorporation of guar gum or locust bean gum," Polymers, vol. 15, no.7, p. 1751, 2023.

A. H. Dawam Abdullah, B. Firdiana, R. Choerun Nissa, R. Satoto, M. Karina, D. Fransiska, Nurhayati, Agusman, H. E. Irianto, P. Priambudi, S. Marliah and Ismadi, "Effect of k-carrageenan on mechanical, thermal and biodegradable properties of starch–carboxymethyl cellulose (CMC) bioplastic," Cellulose Chemistry and Technology, vol. 55, pp. 1109-1117, 2021.

M. Zhang, B. Yang, Z. Yuan, Q. Sheng, C. Jin, J. Qi, M. Yu, Y. Liu, G. Xiong, "Preparation and performance testing of corn starch/pullulan/gallic acid multicomponent composite films for active food packaging," Food Chemistry: X, vol. 19, p. 100782, 2023.

M. Leon-Bejarano, Y. Durmus, M. Ovando-Martínez, and S. Simsek, "Physical, barrier, mechanical, and biodegradability properties of modified starch films with nut by-products extracts," Foods, vol. 9, no. 2, p. 226, 2020.

N. Noivoil and R. Yoksan, "Compatibility improvement of poly(lactic acid)/thermoplastic starch blown films using acetylated starch," Journal of Applied Polymer Science, vol. 138, no. 2, p. 49675, 2020.

A. A. Abdillah and A. L. Charles, "Characterization of a natural biodegradable edible film obtained from arrowroot starch and iota-carrageenan and application in food packaging," International Journal of Biological Macromolecules, vol. 191, pp. 618-626, 2021.

A. Hartiati, B. A. Harsojuwono, H. Suyanto, and I. W. Arnata, "Characteristics of starch-based bioplastic composites in the ratio variations of the polysaccharide mixture," International Journal of Pharmaceutical Research, vol. 13, no. 2, 2021.

L. Fitriani, H. Fadina, H. Usman, and E. Zaini, "Formation and characterization of multicomponent crystal of trimethoprim and mandelic acid by solvent drop grinding method," International Journal of Applied Pharmaceutics, pp. 75-79, 2023.

H. Bai, R. Kumar, C. Yang, X. Liu, and L. Zhang, "Effect of salicylic acid on the mechanical properties and water resistance of soy protein isolate films," Polymers and Polymer Composites, vol. 18, no. 4, pp. 197-203, 2010.

S. Nachiappan, L. Amanuel, T. Agazie, and S. Bihonegn, "Development and characterization of silk films for burn wound healing," Research Journal of Textile and Apparel, vol. 24, pp. 131-146, 2020.

P. Moonsungnoen, D. Ochaikul, and P. Monvisade, "Bacterial cellulose and bacterial cellulose/chitosan films containing mangosteen pericarp extract for wound dressings," Chiang Mai Journal of Science, vol. 48, no. 4, pp. 952-968, 2021.

M. Puccetti, A. Donnadio, M. Ricci, L. Latterini, G. Quaglia, D. Pietrella, A. D. Michele and V. Ambrogi, "Alginate Ag/Agcl nanoparticles composite films for wound dressings with antibiofilm and antimicrobial activities," Journal of Functional Biomaterials, vol. 14, no. 2, p. 84, 2023.

Y. Fang, J. Fu, C. Tao, P. Liu, and B. Cui, "Mechanical properties and antibacterial activities of novel starch-based composite films incorporated with salicylic acid," International journal of biological macromolecules, vol. 155, pp. 1350-1358, 2020.

X. Hu, L. Yuan, L. Han, S. Li, and L. Song, "Characterization of antioxidant and antibacterial gelatin films incorporated with Ginkgo biloba extract," RSC advances, vol. 9, no. 47, pp. 27449-27454, 2019.

T. J. Gutiérrez, P. G. Seligra, C. M. Jaramillo, L. Famá, and S. Goyanes, "Effect of filler properties on the antioxidant response of thermoplastic starch composites," Handbook of composites from renewable materials, structure and chemistry, V. K. Thakur, M. K. Thakur and M. R. Kessler, Eds. New Jersey: Wiley, 2017, pp. 337-370.

K. M. Zepon, M. M. Martins, M. S. Marques, J. M. Heckler, F. D. P. Morisso, M. G. Moreira, A. L. Ziulkoski and L. A. Kanis, "Smart wound dressing based on κ–carrageenan/locust bean gum/cranberry extract for monitoring bacterial infections," Carbohydrate polymers, vol. 206, pp. 362-370, 2019.

Downloads

Published

2024-06-04

How to Cite

[1]
W. SRIPHOCHAI and J. . PRACHAYAWARAKORN, “Natural wound dressing films prepared from acetylated starch/κ-carrageenan blend incorporated with mandelic acid”, J Met Mater Miner, vol. 34, no. 2, p. 1984, Jun. 2024.

Issue

Vol. 34 No. 2 (2024): June

Section

Original Research Articles

License

Copyright (c) 2024 Journal of Metals, Materials and Minerals

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Authors who publish in this journal agree to the following terms:

    1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.

 

    1. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.