Utilization of freeze thaw process for polyvinyl alcohol/sodium alginate (PVA/SA) hydrogel composite

Rapeepan MUANGSRI; Piyachat CHUYSINUAN; Thanyaluck THANYACHAROEN; Supanna TECHASAKUL; Pongpat SUKHAVATTANAKUL; Sarute UMMARTYOTIN

doi:10.55713/jmmm.v32i2.1257

Authors

Rapeepan MUANGSRI Department of Materials and Textile Technology, Faculty of Science and Technology, Thammasat University, Pathumtani, Thailand
Piyachat CHUYSINUAN Laboratory of Organic Synthesis, Chulabhorn Research Institute, Bangkok, Thailand
Thanyaluck THANYACHAROEN Laboratory of Organic Synthesis, Chulabhorn Research Institute, Bangkok, Thailand
Supanna TECHASAKUL Laboratory of Organic Synthesis, Chulabhorn Research Institute, Bangkok, Thailand
Pongpat SUKHAVATTANAKUL Department of Materials and Textile Technology, Faculty of Science and Technology, Thammasat University, Pathumtani, Thailand
Sarute UMMARTYOTIN Department of Materials and Textile Technology, Faculty of Science and Technology, Thammasat University, Pathumtani, Thailand

DOI:

https://doi.org/10.55713/jmmm.v32i2.1257

Keywords:

Hydrogel, Composite, Polyvinyl alcohol, Sodium alginate, Freeze thaw

Abstract

Polyvinyl alcohol/sodium alginate (PVA/SA) hydrogel was successfully prepared by freeze thaw process. Without crosslinking agent, hydrogel was formed by using 3, 5 and 7 consecutive cycles of freeze thaw. Hydrogel can be formed by hydrogen bonding formation between OH-group of sodium alginate and polyvinyl alcohol throughout network. Scanning electron microscope reported that microstructure of hydrogel was well packed. The interconnect porosity was also observed. Differential scanning calorimetry exhibited that two exothermic peaks at temperature of 110℃ and 225℃ were observed due to evaporation of water molecule and melting temperature of hydrogel, respectively. The swelling behavior was rapidly increased within initial stage and then it was dimensionally stable. With low sodium alginate content, tensile strength was slightly superior, whereas low in vitro degradation behavior was observed. It was remarkable to note that polyvinyl alcohol/sodium alginate (PVA/SA) hydrogel exhibited outstanding properties for being as a medical material.

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